laboratory equipment Microscope in blue tone

RaeSedo Inc. awarded $3.4M STTR Grant to Develop New Asthma Therapies

RaeSedo Inc., a spin-out of the University of Arizona developing novel therapies for asthma, is pleased to announce the award of a Phase 2 Small Business Technology Transfer (STTR) grant awarding $3.4 million over two years to continue developing potential therapeutics. Founded and led by researchers from the University of Arizona, RaeSedo Inc. moves into this next…

Microscopic image of lung tissue from SP-A deficient (SP-A-/-) mice showing airway inflammation and structural changes, highlighting the absence of surfactant protein-A's protective effects against inflammation.

Small Peptide Derivatives Within the Carbohydrate Recognition Domain of SP-A2 Modulate Asthma Outcomes in Mouse Models and Human Cells

Surfactant Protein-A (SP-A) is an innate immune modulator that regulates a variety of pulmonary host defense functions. We have shown that SP-A is dysfunctional in asthma, which could be partly due to genetic heterogeneity. In mouse models and primary bronchial epithelial cells from asthmatic participants, we evaluated the functional significance of a particular single nucleotide…